Peer-Reviewed Publication
Quant Imaging Med Surg2026;16(10):802.October 1, 2026Journal Article

Quantification of plaque and detection of high-risk plaque characteristics based on coronary computed tomography angiography: comparison between superresolution deep learning reconstruction and hybrid iterative reconstruction.

Limiao Zou1, Keting Xu1, Xiaohuan Liu2, Cheng Xu1, Haipeng Liu2, Ying Li3, Ying Li4, Tao Zhou4, Lin Yang5, Chunli Zhao6, Na Li7, Yi Lv8, Wenli Hong9, Bo Wang10, Lijun Chen11, Min Xu12, Yufei Li13, Yunxin Zhong13, Zhiping Zhong11, Jikun Zheng10, Zhihua Wu9, Hongzhong Mo8, Tong Zhang7, Demao Deng6, Yaliang Liu5, Shouqiang Jia4, Shaofei He3, Changhua Liang2, Yining Wang1
1Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
2Department of Radiology, The First Affiliated Hospital of Henan Medical University, Weihui, China.
3Department of Radiology, People's Hospital of Mengzi City, Mengzi, China.
4Department of Radiology, People's Hospital Affiliated to Shandong First Medical University, Jinan, China.
5Department of Radiology, Hanzhong Central Hospital, Hanzhong, China.
6Department of Radiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
7Department of Radiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
8Department of Radiology, The First People's Hospital of Yulin, Yulin, China.
9Department of Radiology, The Fourth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
10Department of Radiology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, China.
11Department of Radiology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
12Scientific Collaboration, Canon Medical Systems China, Beijing, China.
13Research and Development Center, Canon Medical Systems China, Beijing, China.

Abstract

BACKGROUND: In addition to stenosis evaluation, coronary computed tomography angiography (CCTA) also allows for noninvasive plaque quantification and characterization, which informs risk stratification and management strategies. This study aimed to compare a novel superresolution deep learning reconstruction (SR-DLR) technique with a conventional hybrid iterative reconstruction (HIR) method in qua…

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