Peer-Reviewed Publication
Magn Reson Med2026October 8, 2026Journal Article

An Inline-Integrable Image Restoration Model With ROI Fine-Tuning and Slice-to-Volume Reconstruction for Accelerated Whole-Brain Vessel Wall Imaging.

Pengcheng Wang1,2, Jingxiang Zhang1,2, Jiayu Xiao1, Junzhou Chen1,3, Zhenjia Wang4, Jin Li5, Qingle Kong1, Steven Y Cen1, Sophia X Cui6, Yifei Zhang7, Wei Yu4, Qi Yang5, Nasim Sheikh-Bahaei1, William J Mack8, Zhaoyang Fan9
1Department of Radiology, University of Southern California, Los Angeles, California, USA.
2Department of Biomedical Engineering, University of Southern California, Los Angeles, California, USA.
3Department of Bioengineering, University of California Los Angeles, California, Los Angeles, California, USA.
4Department of Radiology, Anzhen Hospital, Beijing, China.
5Department of Radiology, Chaoyang Hospital, Beijing, China.
6Siemens Medical Solutions, Los Angeles, California, USA.
7GE HealthCare, Beijing, China.
8Department of Neurological Surgery, University of Southern California, Los Angeles, California, USA.
9Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.

Abstract

PURPOSE: To develop a vessel wall imaging (VWI)-dedicated image restoration model enabling high-resolution whole-brain VWI in under 6 min. METHODS: A transformer-based 2.5D model was trained in a supervised manner to enhance the image quality of CAIPIRINHA 2 × 2-accelerated VWI acquisitions to a level comparable to that of GRAPPA twofold-accelerated scans. The majority of k-space data used for tr…

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