Health AI Central
Peer-Reviewed Publication
NMR Biomed2026;39(11):e70422.November 1, 2026Journal Article

Continuous Imaging of the Cardiac Cycle Metabolism With Hyperpolarized [1-13C]Pyruvate.

Mohsen Redda1,2, Nikolaj Bøgh1,3, Esben Søvsø Szocska Hansen1, Uffe Kjærgaard1,4,5, Rolf F Schulte6, Christoffer Laustsen1
1The MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
2Department of Surgery, Randers Regional Hospital, Randers, Denmark.
3Department of Surgery and Intensive Care, Viborg Regional Hospital, Viborg, Denmark.
4Department of Surgery, Horsens Regional Hospital, Horsens, Denmark.
5Department of Surgery, Aarhus University Hospital, Aarhus, Denmark.
6GE HealthCare, Munich, Germany.
PubMed DOI

Abstract

Hyperpolarized (HP) 13C MRI enables noninvasive assessment of myocardial metabolism. Current approaches typically acquire data only during diastole, ignoring phase-dependent metabolic changes. This study aimed to develop an imaging technique to capture HP [13C]bicarbonate production across both systole and diastole in healthy porcine hearts under rest and stress conditions. Six Danish domestic pig…

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