Health AI Central
Peer-Reviewed Publication
J Magn Reson Imaging2026October 2, 2026Journal Article

Diffusion Basis Spectrum Imaging (DBSI): A Multicompartment Diffusion Model Linking Regional Microstructural Heterogeneity With Proliferation and Survival in High-Grade Gliomas.

Nengjin Zhu1, Liwei Mazu1, Zuqi Xia1, Siyuan He1, Yingqian Huang1, Rulin Xu2, Longfei Zhao3, Shanmei Zeng1, Kejun He4, Jianping Chu1
1Department of Radiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
2Clinical Science Research Department, CT & MR Business Division, Canon Medical Systems, Guangzhou, Guangdong, China.
3Research and Development Center, Canon Medical Systems, Beijing, China.
4Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
PubMed DOI

Abstract

BACKGROUND: Diffusion basis spectrum imaging (DBSI) has emerged as an advanced model capable of characterizing central nervous system tissue injury and glioma pathology. However, the associations of DBSI with key characteristics of high-grade gliomas (HGGs), including proliferation and survival outcomes, remain underexplored. PURPOSE: To evaluate the associations between DBSI-derived histogram fe…

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