Peer-Reviewed Publication
J Magn Reson Imaging2026September 30, 2026Journal Article

Restricted Spectrum Imaging for Diagnosis of High-Risk Metabolic Dysfunction-Associated Steatohepatitis.

Jie Yuan1, Huamei Yan2, Zhiwei Qin3, Liping You4, Guangda Liu3, Wei Xu1, Zheng Tu1, Jinghao Zhang4, Xuehua Sun4, Wenli Tan1
1Department of Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
2Clinical Research Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
3MR Research Collaboration, Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
4Department of Liver, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Abstract

BACKGROUND: Conventional diffusion MRI inadequately characterizes heterogeneous microstructural changes in metabolic dysfunction-associated steatotic liver disease (MASLD). The optimal restricted spectrum imaging (RSI) model and value for high-risk metabolic dysfunction-associated steatohepatitis (MASH) remain unclear. PURPOSE: To optimize RSI modeling and evaluate its performance for high-risk M…

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