Peer-Reviewed Publication
Acad Radiol2026September 26, 2026Journal Article

Accelerating 7T Gradient-Echo Brain MRI With Generative AI Denoising.

Yixin Wang1, Binxu Li2, Yihao Liang3, Mackenzie Carlson3, Phillip DiGiacomo3, Hossein Moein Taghavi3, Julian Maclaren3, Meghan Bell3, Nancy Pham3, Johannes Hugo Decker3, Michael Lv3, Tie Liang3, Jason Wong3, Elizabeth Mormino4, Victor W Henderson4, Greg Zaharchuk3, Brian Rutt3, Wei Shao5, Marios Georgiadis3, Michael Zeineh6
1Department of Bioengineering, Stanford University, Stanford, California.
2Department of Electrical Engineering, Stanford University, Stanford, California.
3Department of Radiology, Stanford School of Medicine, Stanford, California.
4Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California.
5Department of Electrical & Computer Engineering, University of Florida, Florida.
6Department of Radiology, Stanford School of Medicine, Stanford, California. Electronic address: mzeineh@stanford.edu.

Abstract

RATIONALE AND OBJECTIVES: This study aimed to efficiently denoise short 7 T MRI acquisitions to achieve the image quality of longer scans using a generative Artificial Intelligence (AI) model. MATERIALS AND METHODS: A 7T Conditional Diffusion Model (7TCDM) was trained on an in-house 7T dataset of 11 examinations consisting of multi-repetition 2D T2-weighted gradient-echo acquisitions. The model u…

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