Health AI Central
Peer-Reviewed Publication
Circ Cardiovasc Interv2026;e017300.September 23, 2026Journal Article

Artificial Intelligence-Derived Volumetric High-Risk Plaque Features Are Predominantly Located Proximal to Maximal Luminal Stenosis.

Leah Heil1,2, Thijs J Luttikholt1,2, Joske L van der Zande1,2, Jan-Quinten Mol1, Ruben G A van der Waerden1,2, Pierandrea Cancian3,4, Xiaojin Gu3,4, Clara I Sánchez3,4, Bram van Ginneken2, Ivana Išgum5,6, Simone Saitta3,4,7, Jos Thannhauser1,2, Niels van Royen1, Rick H J A Volleberg1
1Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands (L.H., T.J.L., J.L.v.d.Z., J.-Q.M., R.G.A.v.d.W., J.T., N.v.R., R.H.J.A.V.).
2Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, the Netherlands (L.H., T.J.L., J.L.v.d.Z., R.G.A.v.d.W., B.v.G., J.T.).
3Department of Biomedical Engineering and Physics (P.C., X.G., C.I.S., S.S.), Amsterdam University Medical Center, the Netherlands.
4Informatics Institute, University of Amsterdam, the Netherlands (P.C., X.G., C.I.S., S.S.).
5Department of Radiology and Nuclear Medicine (I.I.), Amsterdam University Medical Center, the Netherlands.
6Department of Radiology, Mayo Clinic, Rochester, MN (I.I.).
7Amsterdam Cardiovascular Sciences, Amsterdam University Medical Center, the Netherlands (S.S.).
PubMed DOI

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