Real-World Systemic Treatment Outcomes for Moderate-to-Severe Atopic Dermatitis in Children by Skin Color: 4-Year Results from the observational, international, real-world PEDISTAD Registry.

Amy S Paller¹, Lawrence F Eichenfield², Lara Wine Lee³, Michele Ramien⁴, Lin Ma⁵, Yuri Igor López Carrera⁶, Joel C Joyce⁷, Mercedes E Gonzalez⁸, Korey Capozza⁹, Sara Hamad¹⁰, Marius Ardeleanu¹¹, Annie Zhang¹²

¹Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago; Division of Dermatology, Ann & Robert H. Lurie Children's Hospital, Chicago. Electronic address: apaller@northwestern.edu.

²Departments of Dermatology and Pediatrics, University of California San Diego School of Medicine, La Jolla; Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital, San Diego.

³Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston.

⁴Section of Community Pediatrics, Department of Pediatrics, Alberta Children's Hospital, Calgary; Division of Dermatology, Department of Medicine, University of Calgary, Calgary.

⁵Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing.

⁶Hospital Angeles Puebla, Puebla.

⁷Division of Dermatology, Department of Medicine, Endeavor Health, Skokie.

⁸Pediatric Skin Research, Coral Gables.

⁹Global Parents for Eczema Research, Santa Barbara.

¹⁰Cytel - Evidence Generation & Decision Science, London.

¹¹Regeneron Pharmaceuticals Inc., Tarrytown.

¹²Sanofi, Cambridge.

PubMed DOI

Abstract

BACKGROUND: Atopic dermatitis (AD) can have different genetic, immunopathogenic, and clinical features depending on the ethnicity of the affected individual. OBJECTIVE: To investigate if White and non-White children with moderate-to-severe AD respond differently to systemic treatment. METHODS: PEDISTAD is an observational, international, real-world study. Patients were analyzed in two subgroups:…

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