Psychiatric outcomes after streptococcal upper respiratory tract infection in children.

Danish Hafeez¹, Katharine Lynch-Kelly¹, Cameron Watson², Sarah Williford³, Mark Edwards⁴, Thomas A Pollak¹

¹Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

²MRC Social Genetic and Developmental Psychiatry Research Centre: King's College London, UK.

³TriNetX LCC, Cambridge, USA.

⁴Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience: King's College London, UK.

PubMed DOI

Abstract

BACKGROUND: Associations between childhood streptococcal upper respiratory infections and subsequent psychiatric outcomes have been described for over 25 years, although clinical evidence remains limited. This study explored psychiatric outcomes after pediatric streptococcal versus non-streptococcal upper respiratory tract infections. METHODS: This retrospective cohort study used TriNetX, a globa…

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