Health AI Central
Peer-Reviewed Publication
Front Neurol2026;171756028.January 1, 2026Journal Article

Deep learning-based susceptibility map-weighted imaging analysis of dorsal nigral hyperintensity as a surrogate for dopamine transporter positron emission tomography in patients with idiopathic rapid eye movement sleep behavior disorder.

Beomseok Sohn1, Jae Rim Kim2, Hwan Heo3, Soohwa Song3, Eung Yeop Kim1, Eun Yeon Joo4
1Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
2Department of Neurology, Chungnam National University Sejong Hospital, Sejong, Republic of Korea.
3Heuron Co., Ltd., Seoul, Republic of Korea.
4Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
PubMed PMC DOI PDF

Abstract

Idiopathic REM sleep behavior disorder (iRBD) is a prodromal stage of alpha-synucleinopathies, and accurate identification of early dopaminergic dysfunction is clinically important. This study evaluated whether deep learning-based susceptibility map-weighted imaging (SMwI) can predict dopamine transporter (DAT) positron emission tomography (PET) abnormalities in patients with iRBD. We retrospectiv…

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