Health AI Central
Peer-Reviewed Publication
Eur J Neurosci2026;64(5):e70678.September 1, 2026Journal Article

The Effects of Anxiety and Cognitive Load on Freezing of Gait in Parkinson's Disease.

Demi Zoetewei1, Moran Gilat1, Nicholas D'Cruz1, Jan Cornelis2, Jordan Bedime Songue Njiki3, Rick C Helmich4, Pieter Ginis1,5, Alice Nieuwboer1
1Department of Rehabilitation Sciences, Neurorehabilitation Research Group (eNRGy), KU Leuven, Leuven, Belgium.
2Imec, Heverlee, Belgium.
3Department of Kinesiology & Physical Education, McGill University, Montréal, Québec, Canada.
4Donders Institute for Brain, Cognition and Behavior, Department of Neurology, Centre of Expertise for Parkinson and Movement Disorders, Radboud University Medical Centre, Nijmegen, the Netherlands.
5Clario, Part of Thermo Fisher Scientific, Leuven, Belgium.
PubMed PMC DOI PDF

Abstract

It is currently unclear whether anxiety, cognitive load, or their combination modulates freezing of gait differently and whether people with Parkinson's disease and freezing of gait (freezers) suffer from stronger threat responsiveness than nonfreezing groups. Therefore, we investigated 28 freezers, 19 nonfreezers, and 19 healthy age-matched controls, who completed a freezing-provoking protocol un…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Create Free AccountSign In

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.