Peer-Reviewed Publication
J Pathol Inform2026;22100693.August 1, 2026Journal Article

Comparison and image analysis of different file formats on whole-slide images for colorectal and non-small cell lung carcinomas.

Monika Lamba Saini1, Darshan Kumar2, Andreea Luchian2, Hazel Smith3, John D Cochran4
1ADC Therapeutics, iHub, Imperial College White City, London W12 0BZ, UK.
2Aiforia Technologies, Pursimiehenkatu 29-31 D, FI-00150 Helsinki, Finland.
3IQVIA Laboratories, The Alba Campus, Rosebank, Livingston EH54 7EG, UK.
4IQVIA Laboratories, 1600 Terrell Mill Road, Suite 100, Marietta, GA 30067, USA.

Abstract

Different scanners employ various image acquisition techniques and may store scanned images in proprietary formats or export them to a range of standard file formats. Understanding these technical limitations is essential for ensuring optimal scan quality and accurate image analysis. The present study compared image formats from two whole-slide imaging platforms-Leica's Aperio AT2 (.SVS) and 3DHis…

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