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Peer-Reviewed Publication
J Am Heart Assoc2026;e048351.August 20, 2026Journal Article

Serial Computed Tomography Perfusion and Diffusion Imaging After Complete Recanalization in Large-Vessel Occlusion.

Nakhoon Kim1, Wi-Sun Ryu2, Leonard Sunwoo3, Younbeom Jeong3, Jun Yup Kim1, Jihoon Kang1, JoonNyung Heo4, Sung Hyun Baik3, Cheolkyu Jung3, Moon-Ku Han1,5, Hee-Joon Bae1,5, Baik Kyun Kim1,6, Johanna Ospel7, Longting Lin8, Mark Parsons8, Beom Joon Kim1
1Department of Neurology Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do Republic of Korea.
2Artificial Intelligence Research Center JLK Inc. Seoul Republic of Korea.
3Department of Radiology Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do Republic of Korea.
4Department of Neurology Yonsei University College of Medicine Seoul Republic of Korea.
5Department of Neuroscience Seoul National University College of Medicine Seoul Republic of Korea.
6Department of Neurology Gyeonggi Provincial Medical Center Icheon Hospital Icheon Republic of Korea.
7Calgary Stroke Program, Department of Clinical Neurosciences and Community Health Sciences, The Hotchkiss Brain Institute and the O'Brien Institute for Public Health University of Calgary Calgary AB Canada.
8Department of Neurology Liverpool Hospital, University of New South Wales, School of Clinical Medicine, South Western Sydney Clinical Campus Sydney NSW Australia.

Abstract

BACKGROUND: Infarct evolution on diffusion-weighted imaging (DWI) after complete recanalization and its relationships to computed tomography perfusion core and outcome remain uncertain. METHODS: From a multicenter registry (2014-2024), we identified 189 patients with anterior-circulation large-vessel occlusion, modified Thrombolysis in Cerebral Infarction grade 3 recanalization, prethrombectomy c…

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