Assessment of atypical glandular cell interpretation in Pap tests using the Hologic Genius Digital Diagnostics System.

Terri E Jones¹, Jonee Matsko¹, Daisy Wu¹, Xianxu Zeng², Amy Colaizzi¹, Haley Brown¹, Liron Pantanowitz¹, Chengquan Zhao¹

¹Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

²Department of Pathology, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

PubMed DOI

Abstract

Atypical glandular cells (AGC) are a diagnostic challenge. The aim of this study was to evaluate the efficacy and diagnostic performance of AGC detection on the Hologic Genius Digital Diagnostics System (HGDDS). A retrospective analysis of 451 ThinPrep Pap cases was conducted, including 207 cases of AGC, 27 cases of high-grade squamous intraepithelial lesion (HSIL), 25 cases of low-grade squamous…

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