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Peer-Reviewed Publication
Open Forum Infect Dis2026;13(7):ofag449.July 1, 2026Journal Article

Individual-level Factors Associated With Acute Hospitalization After Medically Attended Acute Gastroenteritis and Norovirus Gastroenteritis in the United States, 2022-2024.

John Shen1, Christine Kim2, Christopher Bush1, Wen-Hsing Wu2, Caroline Bridges1, Allison E Olmsted3, Julia M Baker3, Brandon J Patterson2, Ben A Lopman3,4, Daniel C Payne3,5, Evan J Anderson2, Katherine B Carlson2
1Life Sciences, Datavant, Inc., Phoenix, Arizona, USA.
2Moderna, Inc., Cambridge, Massachusetts, USA.
3Epidemiologic Research and Methods, LLC, Atlanta, Georgia, USA.
4Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
5Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Abstract

BACKGROUND: Norovirus is a leading cause of acute gastroenteritis (AGE) in the United States and is associated with substantial healthcare utilization, including risk of hospitalization. The extent to which underlying medical conditions contribute to this risk is not well understood. METHODS: This retrospective cohort study analyzed adults with incident medically attended all-cause AGE or cause-s…

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