Peer-Reviewed Publication
Radiology2026;320(1):e252433.July 1, 2026Journal Article

Contrast-enhanced Mammography for Breast Cancer Screening in Women at Increased Risk: Comparison of Prevalence and Incidence Screens.

Carol H Lee1, Tali Amir1, Varadan Sevilimedu2, Sarah Eskreis-Winkler1, Delia Keating1,3, Donna D'Alessio1, Maxine S Jochelson1,4, Gordon P Watt2,5, Kimberly N Feigin1, Noam Nissan1,6, Hila Fruchtman-Brot1,7, Christopher E Comstock1,8, Janice S Sung1,3
1Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY.
2Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
3Department of Radiology, Columbia University, New York, NY.
4Breastlink Women's Imaging, RADNET Beverly Hills, Los Angeles, Calif.
5The Netherlands Cancer Institute, Amsterdam, the Netherlands.
6Department of Radiology, Sheba Medical Center, Tel Hashomer, Israel.
7Department of Radiology, NYU Langone Health, New York, NY.
8Department of Radiology, New York-Presbyterian/Weill Cornell Medical Center, New York, NY.

Abstract

Background Studies have reported the value of contrast-enhanced mammography (CEM) for screening women at increased risk for breast cancer, based on prevalence ("baseline") screening. Purpose To compare the performance of CEM between prevalence and incidence screens in women at increased risk for breast cancer. Materials and Methods This retrospective study included CEM screens from January 2015 th…

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