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Peer-Reviewed Publication
Pediatr Blood Cancer2026;e70538.July 25, 2026Letter

Early Acute Leukemia Relapse After CD19-Directed CAR-T With Lineage Switch From B to T-ALL in a Pediatric Patient.

Yannan J Wang1, Nefeli Beri2, Sam Sirotnikov3,4, Ilan Kirsch5, Rakesh Awasthi6, Robin Dulman7, Anant Vatsayan4,8, Jingbo Gao6, Hans Menssen9, Reuven J Schore1,4, Jennifer Willert6, Keri Toner1,4
1Cancer and Blood Disorders Center, Children's National Hospital, Washington, District of Columbia, USA.
2Novartis Pharmaceuticals, Basel, Switzerland.
3Department of Pathology and Laboratory Medicine, Children's National Hospital, Washington, District of Columbia, USA.
4George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
5Adaptive Biotechnologies, Seattle, Washington, USA.
6Novartis Pharmaceuticals, New Jersey, USA.
7Center for Cancer and Blood Disorders, Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
8Division of Blood and Marrow Transplantation, Children's National Hospital, Washington, District of Columbia, USA.
9Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine, Berlin, Germany.
PubMed DOI

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