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Peer-Reviewed Publication
Adv Radiat Oncol2026;11(11):102084.November 1, 2026Journal Article

Multimodality Multimask and Multitask Auto-Segmentation Network for Organs-at-Risk in Head and Neck Radiation Therapy.

Xiaochen Ni1, Tianci Tang1, Shengwei Li1, Lecheng Jia2, Ziquan Wei2, Yi Zhu1, Ji Li1, Weifang Wang1, Xinmao Song1, Lifen Zou1, Haiyan Zhang1, Shu Tian1, Li Yan1, Gang Yang1, Fu Chen1, Tian Wang1, Li Wang1, Jie Wang1, Ruichen Li1, Siyuan Ma1, Xiaoshen Wang1
1Department of Radiotherapy, Eye & ENT Hospital of Fudan University, Shanghai, China.
2Radiotherapy Business Unit, Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China.

Abstract

PURPOSE: Accurate segmentation of head and neck organs-at-risk remains a critical challenge in radiation therapy planning, where current single-modality approaches often fail to address the inherent complexity of soft-tissue differentiation and interpatient anatomic variations. This study aims to develop a clinically robust auto-segmentation framework that synergistically integrates multimodal ima…

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