Health AI Central
Peer-Reviewed Publication
Nat Health2026May 22, 2026Journal Article

A framework for longitudinal health AI agents.

Georgianna Lin1, Rencong Jiang2, Noémie Elhadad1, Xuhai 'Orson' Xu1
1Columbia University, Biomedical Informatics, New York, NY, USA.
2Columbia University, Computer Science, New York, NY, USA.
PubMed PMC DOI PDF

Abstract

Although artificial intelligence (AI) agents are increasingly proposed to support potentially longitudinal health tasks, such as symptom management, behaviour change and patient support, most current implementations fall short of facilitating user intent and fostering accountability. This contrasts with prior work on supporting longitudinal needs, both within and beyond clinical settings, where fo…

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