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Peer-Reviewed Publication
Menopause2026July 14, 2026Journal Article

Exploring prevalence and drivers of perimenopause uncertainty among US Women: a mixed-methods study.

Yihan Xu1, Deirbhle Fergus1,2,3, Yella Hewings-Martin1, Mary Hedges4, Carley Prentice1, Adam Cunningham1, Liudmila Zhaunova1, Chrisandra Shufelt4,5, Stephanie Faubion4,5
1Flo Health Inc., London, UK.
2Institute of Epidemiology & Health, University College London, London, UK.
3School of Population Health, Royal College of Surgeons in Ireland, Dublin, Ireland.
4Department of Medicine, Mayo Clinic, Jacksonville, FL.
5Center for Women's Health, Mayo Clinic, Rochester, MN.

Abstract

OBJECTIVE: Perimenopause is an under-recognized life stage that is often accompanied by complex and fluctuating symptoms. We aimed to quantify the prevalence of perimenopause uncertainty and explore the underlying drivers. METHODS: We conducted a mixed-methods study using a cross-sectional survey of US women aged 35 years and above (N=7,640). We estimated the prevalence of perimenopause uncertain…

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