Retrospective Analysis of a WashU-Based Knowledge-Based Planning (KBP) Model for Breast and Chest Wall Planning in Guatemala: Compliance With American Society for Radiation Oncology (ASTRO) 2026 Guidelines.

Milton E Ixquiac Cabrera^1,2, Erick O Montenegro², Matthew Schmidt³, Baozhou Sun⁴, James A Kavanaugh⁵, Taoran Li⁶, Angel Velarde⁷, Vicky de Falla², Francisco Reynoso⁸

¹School of Physical and Mathematical Sciences, Universidad de San Carlos de Guatemala, Guatemala, GTM.

²Radiotherapy, Liga Nacional Contra el Cáncer, Guatemala, GTM.

³Radiation Oncology, Washington University School of Medicine, St. Louis, USA.

⁴Medical Physics, Baylor College of Medicine, San Antonio, USA.

⁵Radiation Oncology, Mayo Clinic, Rochester, USA.

⁶Department of Radiation Oncology, University of Pennsylvania, Philadelphia, USA.

⁷Oncology, Oncological Hospital Incan, Guatemala, GTM.

⁸Medical Science Liaison, Varian Medical Systems, Schiller Park, USA.

PubMed PMC DOI PDF

Abstract

Background/purpose Breast cancer is among the most prevalent malignancies treated at the Liga Nacional Contra el Cáncer (LNCC) in Guatemala, representing a significant proportion of annual radiotherapy cases. Access to high-quality, standardized treatment planning in resource-constrained settings remains a critical challenge. This study evaluates the dosimetric performance of knowledge-based plann…

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