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Peer-Reviewed Publication
Ther Adv Gastroenterol2026;1917562848261462398.January 1, 2026Journal Article

Using artificial intelligence to identify characteristics associated with clinical and economic outcomes in MASH (FOCUS-MASH).

Kamal Kant Mangla1, Semiu O Gbadamosi2, Daniel Semeniuta3, Jigar Bandaria3, Joseph Zabinski3, Gary Curhan3, Costas Boussios3
1Novo Nordisk Service Centre India Pvt. Ltd., Bengaluru, KA 560066, India.
2Novo Nordisk Inc., Plainsboro, NJ, USA.
3OM1, Inc., Boston, MA, USA.

Abstract

BACKGROUND: Heterogeneity in the disease characteristics of metabolic dysfunction-associated steatohepatitis (MASH) complicates efforts to identify individuals with high unmet need. OBJECTIVE: We used artificial intelligence (AI) phenotyping to identify factors associated with rapid fibrosis progression, long-term clinical outcomes, and high healthcare costs. DESIGN: In this retrospective cohort…

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