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Peer-Reviewed Publication
Virchows Arch2026June 3, 2026Journal Article

An artificial intelligence solution for evaluation of prostate needle core biopsy specimens: impact in a non-specialist setting.

Gerald Niedobitek1,2, Gernot Schmitz3, Manuel Fella3, André Oliveira3, John Theunissen4, Manuela Vecsler4, Jens Köllermann5
1Institute for Pathology, Sana Klinikum Lichtenberg, Berlin, Germany. niedobitekg@gmail.com.
2Institut für Pathologie, Klinikum Ernst von Bergmann, Charlottenstr. 72, 14467, Potsdam, Germany. niedobitekg@gmail.com.
3Institute for Pathology, Sana Klinikum Lichtenberg, Berlin, Germany.
4Ibex Medical Analytics, Tel Aviv, Israel.
5Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt/M, Germany.

Abstract

The diagnosis of prostate cancer rests on the histopathological evaluation of prostate needle core biopsy specimens (NCBS) supplemented by immunohistochemistry as required. Because of the well-known interobserver variability in diagnosis and grading of prostate cancer, we have studied the capability of a commercially available artificial intelligence (AI) solution to aid in the diagnosis of PCa in…

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