Applications of artificial intelligence in nuclear medicine.

Lena Kaiser¹, Thomas Wendler², Deni Hardiansyah³, Dirk Hellwig⁴, Philipp Lohmann⁵, Stephan Nekolla⁶, Laszlo Papp⁷, Philipp Ritt⁸, Lalith Kumar Shiyam Sundar⁹, Johannes Tran-Gia¹⁰, Artem Zatcepin¹¹, Isabelle Miederer¹²

¹Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany. Electronic address: lena.kaiser@med.uni-muenchen.de.

²Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Augsburg, Augsburg, Germany; Digital Medicine, University Hospital Augsburg, Neusaess, Germany; School of Computation, Information and Technology, Technical University of Munich, Garching bei München, Germany.

³Medical Physics and Biophysics, Physics Department, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.

⁴Department of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany; Partner Site Regensburg, Bavarian Cancer Research Center, Regensburg, Germany; Medical Data Integration Center (MEDIZUKR), University Hospital Regensburg, Regensburg, Germany.

⁵Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich, Jülich, Germany; Department of Nuclear Medicine, RWTH Aachen University Hospital, Aachen, Germany.

⁶Department of Nuclear Medicine, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

⁷Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

⁸Friedrich-Alexander-Universität Erlangen-Nürnberg, Chair for Clinical Nuclear Medicine, 91054 Erlangen, Germany.

⁹DIGIT-X Lab, Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.

¹⁰Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

¹¹Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

¹²Department of Nuclear Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

PubMed PMC DOI PDF

Abstract

Artificial intelligence (AI) has vast potential to reshape nuclear medicine. Applications can be found at every step of the processing workflow, including image acquisition, image reconstruction, enhancement, and registration, segmentation, extraction of image-derived biomarkers, and prognostication, both for clinical and preclinical research and routine use. Emerging perspectives include computat…

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