Health AI Central
Share:
Peer-Reviewed Publication
Food Chem Toxicol2026;215116131.September 1, 2026Journal Article

Toxicological evaluation of peptide compound TSC6: A 13-week subchronic toxicity and genotoxicity study.

Genwei Zhang1, Xiaolu Huang2, Yujie Fang3, Tongren Liu4, Congling Fan5, Bo Li6, Lipeng Lai7
1XtalPi Holdings Limited, 6025 Shennan Avenue, Futian District, Shenzheng, Guangdong Province, 518048, China. Electronic address: genwei.zhang@xtalpi.com.
2XtalPi Holdings Limited, 6025 Shennan Avenue, Futian District, Shenzheng, Guangdong Province, 518048, China. Electronic address: xiaolu.huang@xtapi.com.
3XtalPi Holdings Limited, 6025 Shennan Avenue, Futian District, Shenzheng, Guangdong Province, 518048, China. Electronic address: yujie.fang@xtalpi.com.
4XtalPi Holdings Limited, 6025 Shennan Avenue, Futian District, Shenzheng, Guangdong Province, 518048, China. Electronic address: tongren.liu@xtalpi.com.
5XtalPi Holdings Limited, 6025 Shennan Avenue, Futian District, Shenzheng, Guangdong Province, 518048, China. Electronic address: fancongling1@126.com.
6The First Affiliated Hospital, Zhejiang University School of Medicine, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, 79 Qingchun Road, Shangcheng District, Hangzhou, Zhejiang Province, 310003, China. Electronic address: suon@zju.edu.cn.
7XtalPi Holdings Limited, 6025 Shennan Avenue, Futian District, Shenzheng, Guangdong Province, 518048, China. Electronic address: lipeng.lai@xtalpi.com.
PubMed DOI

Abstract

TSC6-peptide is an 8-amino acid synthetic peptide compound that inhibits intestinal α-amylase upon oral administration to control the digestion and absorption of starchy foods. However, its toxicological safety and other scientific evidence remain to be established. Given the potential utility of TSC6-peptide as an α-amylase inhibitor, this study conducted in vivo and in vitro experiments to suppo…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Create Free AccountSign In

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.