Peer-Reviewed Publication
Eur J Radiol2026;200112845.July 1, 2026Journal Article
Clinical relevance and reproducibility of morphological MRI findings in liver cirrhosis: Results from ACCESS-ESLD.
Signe Swerkersson1, Wolf Bartholomä2, Mikael F Forsgren3, Henrik Stjernman4, Daniel Sjögren5, Stergios Kechagias6, Patrik Nasr7, Markus Holmberg6, Peter Lundberg8, Martin Rejler9, Olof Dahlqvist Leinhard3, Nils Dahlström2, Mattias Ekstedt10
1Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Campus US, 582 25 Linköping, Sweden; Clinical Department of Radiology, Capio St Göran Hospital, Stockholm, Sweden. Electronic address: signe.swerkersson@liu.se.
2Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Campus US, 582 25 Linköping, Sweden; Clinical Department of Radiology in Linköping, Region Östergötland, Linköping, Sweden.
3Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Campus US, 582 25 Linköping, Sweden; AMRA Medical AB, Linköping, Sweden.
4Department of Internal Medicine, Ryhov Hospital Jönköping, Region Jönköping County Council, Jönköping, Sweden.
5Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden; Department of Medicine, Eksjö Hospital, Region Jönköping County Council, Eksjö, Sweden.
6Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden.
7Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Campus US, 582 25 Linköping, Sweden; Wallenberg Center for Molecular Medicine (WCMM), Linköping University, Campus US, 582 25 Linköping, Sweden.
8Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Campus US, 582 25 Linköping, Sweden; Clinical Department of Radiology in Linköping, Region Östergötland, Linköping, Sweden; Clinical Department of Medical Radiation Physics, Region Östergötland, Linköping, Sweden.
9Department of Internal Medicine, Ryhov Hospital Jönköping, Region Jönköping County Council, Jönköping, Sweden; The Jönköping Academy for Improvement of Health and Welfare, Hälsohögskolan, Jönköping University, Jönköping, Sweden.
10Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, 582 25 Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Campus US, 582 25 Linköping, Sweden.
Abstract
OBJECTIVES: To validate the clinical relevance and reproducibility of morphological features on magnetic resonance imaging (MRI) in liver cirrhosis.
MATERIALS & METHODS: This is a cross-sectional analysis of the baseline MRI examinations in a prospective multi-center study of patients with liver cirrhosis. Two radiologists independently assessed multiple morphological features and the overall deg…
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