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Peer-Reviewed Publication
Eur Heart J Digit Health2026;7(3):ztag047.April 1, 2026Journal Article

Cross-sectional evaluation of cardiovascular biological age using point-of-care ultrasound.

Roi Amster1,2,3, Abigail Goshen1,4, Harel Raanani3,5, Adiel Am-Shalom5, Michael Fiman5, Robert Klempfner2,3,5, Ehud Raanani2,3,5, Ehud Schwammenthal2,3,5, Evelyne Bischof1,3, Elad Maor2,3, Tzipora Strauss1,3
1Sheba Longevity Center, Sheba Medical Center, Ramat Gan, Israel.
2The Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Ramat Gan, Israel.
3Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
4Department of Management, Health Systems Management Program, Bar-Ilan University, Ramat Gan, Israel.
5Aisap.ai, Israel.

Abstract

AIMS: Biological age is increasingly recognized as a superior predictor of morbidity, mortality, compared with chronological age. Artificial intelligence (AI)-driven ageing clocks enable rapid, non-invasive assessment. Cardiovascular (CV) ageing is of particular relevance given its central role in systemic metabolic health. This study evaluated the clinical utility of an ultrasound (US)-based CV b…

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