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Peer-Reviewed Publication
Front Psychol2026;171775489.January 1, 2026Journal Article

Transforming psychological practice with precision mental health: introduction to the NOVA project.

Pablo Roca1,2, Sara Noheda1, Eduar Ramírez-Riveros1,3, Carolina Martín-Azañedo1,3, Fermín Martínez-Zaragoza4, Rosaria Maria Zangri2,5, Eduardo P García Del Valle2,6, Martin Sanchez-Pedreño1,2, Montserrat León-Garcia7, Derek Loy Gravholt7, Angel Enrique8, Rob Saunders9, Luis Javier Herrera10, María Del Carmen Pegalajar11, Carmelo Vázquez12, Sara Rodriguez-Moreno1,13
1Precision Mind Lab (Premind), Universidad Villanueva, Madrid, Spain.
2Medea Lab, Madrid, Spain.
3Universidad Francisco de Vitoria, Pozuelo de Alarcón, Spain.
4Department of Behavioural Sciences and Health, Miguel Hernandez University of Elche (UMH), Alicante, Spain.
5Facultad de Salud, UNIE Universidad, Madrid, Spain.
6School of Science and Technology, IE University, Madrid, Spain.
7Knowledge and Evaluation (KER) Unit, Mayo Clinic, Rochester, MN, United States.
8Amwell Science, Amwell, Boston, MA, United States.
9CORE Data Lab, Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.
10Department of Computer Engineering, Automatics and Robotics, University of Granada, Granada, Spain.
11Department of Computer Science and Artificial Intelligence, University of Granada, Granada, Spain.
12Complutense University of Madrid, Madrid, Spain.
13Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.

Abstract

Evidence-Based Practice (EBP) has increased the availability of psychological treatments, yet many people do not benefit from therapy, some report deteriorations in symptoms, and dropout rates remain high. Precision Mental Health (PMH) is proposed as an extension of EBP by combining systematic measurement with predictive analytics to support the right intervention, at the right time, for the right…

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