Health AI Central
Peer-Reviewed Publication
Adv Sci (Weinh)2026;e00032.March 2, 2026Journal Article

Harnessing Phase Separation for the Development of High-Performance Hydrogels.

Yue Shao1,2, Yiming Ma1, Baihao Shao1,2,3, Molly M Stevens1,2
1Department of Physiology, Anatomy and Genetics, Department of Engineering Science, and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.
2Department of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London, London, UK.
3Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China.
PubMed PMC DOI PDF

Abstract

Hydrogels are indispensable for the development of next-generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by more than just covalent bonds and polymer entanglements. B…

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