Peer-Reviewed Publication
NPJ Digit Med2026;9(1)February 26, 2026Journal Article
Multi night digital assessment of sleep disordered breathing is associated with accelerated vascular aging.
Lucía Pinilla1, Kelly Sansom2,3, Philomène Letzelter4, Andrew Vakulin2, Ashley Montero2, Anna Hudson2, Pierre Escourrou5, Jean-Louis Pepin6, Robert Adams2, Peter Catcheside2, Bastien Lechat2, Danny J Eckert2
1Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute: Sleep Health, Adelaide, SA, Australia. lucia.pinilla@flinders.edu.au.
2Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute: Sleep Health, Adelaide, SA, Australia.
3Centre for Healthy Ageing, Health Futures Institute, Murdoch University, Perth, WA, Australia.
4Withings, Issy-les-Moulineaux, France / Inria, HeKA, PariSantéCampus, Paris, France.
5Centre Interdisciplinaire du Sommeil, Paris, France.
6HP2 Laboratory, Inserm U1300, Grenoble Alpes University, Grenoble, France.
Abstract
Pulse wave velocity (PWV) is a marker of vascular aging and cardiovascular risk. Obstructive sleep apnea (OSA) may accelerate vascular decline, but evidence from single-night assessments is inconsistent. We examined associations of multi-night OSA severity, night-to-night variability, and snoring with arterial stiffness in a real-world setting. Adults used two in-home digital devices over a ~ 4 y…
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