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Peer-Reviewed Publication
Eur Heart J Cardiovasc Imaging2026;27(3):544-553.February 27, 2026Journal Article

Comparing prognostic significance of dual bolus and dual sequence quantitative stress perfusion cardiac magnetic resonance.

Kwan Ho Leung1, Haonan Wang2, Eponine Kate Wong1, Parco Chu1, Tsun Hei Sin1, Jasper Chak Fung Yip1, Romelie M Tuplano1, Wan Man Vivian Tse1, Cheuk Nam Felix Kwan1, Eric Yuk Fai Wan3,4, Chor Cheung Frankie Tam5, Kwong Yue Eric Chan5, Chun Yu Leung6, Victor King-Man Goh7, Konrad Werys8, Randall Stafford9, Martin A Janich10, Ming-Yen Ng1
1Department of Diagnostic Radiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
2GE HealthCare, Waukesha, WI, USA.
3Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR.
4Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR.
5Division of Cardiology, Department of Medicine, Queen Mary Hospital, Hong Kong SAR.
6Department of Medicine, Tseung Kwan O Hospital, Hong Kong SAR.
7Hong Kong Sanatorium & Hospital, Hong Kong SAR.
8Circle Cardiovascular Imaging Inc., Berlin, Germany.
9Circle Cardiovascular Imaging Inc., Calgary, Alberta, Canada.
10GE HealthCare, Munich, Germany.

Abstract

AIMS: Quantitative stress perfusion (QP) cardiac magnetic resonance (CMR) can be performed using the dual sequence (DS) or dual bolus (DB) technique. DS does not require additional contrast and image acquisition but needs a research sequence. DB can be performed on all magnetic resonance imaging (MRI) scanners with standard perfusion sequences but requires additional contrast injection and image a…

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