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Peer-Reviewed Publication
Menopause2026;33(7):789-798.July 1, 2026Journal Article

Global perspectives on perimenopause: a digital survey of knowledge and symptoms using the Flo application.

Mary S Hedges1, Yella Hewings-Martin2, Jana Karam1,3, Regina Castaneda1,3, Adam C Cunningham2, Yihan Xu2, Liudmila Zhaunova2, Stephanie S Faubion1,3, Chrisandra L Shufelt1,3
1Department of Medicine, Mayo Clinic, Jacksonville, FL.
2Flo Health, Inc., London, United Kingdom.
3Center for Women's Health, Mayo Clinic, Rochester, MN.
PubMed DOI

Abstract

OBJECTIVE: Perimenopause is the time leading up to a woman's last menstrual cycle and includes the 12 months afterward. Studies that systematically compare perimenopause symptoms across diverse cultural and geographic settings are lacking. This study, utilizing data from Flo, an international mobile health application, aimed to assess global knowledge and symptom experiences related to perimenopau…

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