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Peer-Reviewed Publication
Equine Vet J2026;58(2):380-389.March 1, 2026Journal Article

Synovial chemokine and cytokine profiles in horses with and without systemic Borrelia burgdorferi infection.

Kyle F Clark1, Rachel A Lemcke2, Janik C Gasiorowski1, Bettina Wagner3
1Mid-Atlantic Equine Medical Center, Ringoes, New Jersey, USA.
2Amwell Data Services LLC, Ringoes, New Jersey, USA.
3Department of Population Medicine and Diagnostic Sciences, Cornell University, Ithaca, New York, USA.

Abstract

BACKGROUND: Lyme arthritis, a well-documented subtype of arthritis in humans and dogs, is caused by Borrelia burgdorferi and spread primarily through ticks (Ixodes spp.). While Lyme disease in horses is known to cause a variety of clinical signs, its involvement in the development of equine arthritis is controversial. As climate change enables tick populations to expand, more horses could be expos…

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