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Peer-Reviewed Publication
Sci Data2025;12(1):1852.November 20, 2025Journal Article

The ICGC ARGO data dictionary for standardizing global cancer clinical data.

Hardeep K Nahal-Bose1, Peter Lichter2, Ursula Weber2, Lincoln D Stein1,3, Rosita Bajari1,4, Linda Xiang1, Edmund Su1, Jon Eubank1, Ciarán Schütte1, Christina K Yung1,5, Mélanie Courtot6,7,8
1Ontario Institute for Cancer Research (OICR), Toronto, ON, M5G 1M1, Canada.
2Division Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
3Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 3K3, Canada.
4Element Biosciences, San Diego, CA, 92121, USA.
5Indoc Systems, Toronto, ON, M5H 3W4, Canada.
6Ontario Institute for Cancer Research (OICR), Toronto, ON, M5G 1M1, Canada. mcourtot@gmail.com.
7Medical Biophysics Department, University of Toronto, Toronto, ON, M5G 2C4, Canada. mcourtot@gmail.com.
8Department of Computer Science, University of Toronto, Toronto, ON, M5S 2E4, Canada. mcourtot@gmail.com.

Abstract

The International Cancer Genome Consortium Accelerating Research in Genomic Oncology (ICGC ARGO) project is an international initiative to sequence germline and tumour genomes from 100,000 cancer patients across 13 countries and 22 tumour types. By integrating genomic data with comprehensive clinical information including treatment outcomes, lifestyle, environmental exposures and family history, I…

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