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Peer-Reviewed Publication
BMJ Open Respir Res2025;12(1)November 17, 2025Journal Article

Employment of artificial intelligence for early lung cancer diagnosis: a retrospective cohort study.

Nathan R Hill1, Travis Dotson2, Sarah E Maus2, Christina Bellinger2, Vishisht Mehta3, Annika Rings4, Lyndsey C Pickup5, Noah Waterfield Price5, Václav Potěšil5, David P Carbone6, Jasleen Pannu7
1Bristol-Myers Squibb Co R&D Lawrenceville, Lawrenceville, New Jersey, USA.
2Pulmonary/Critical Care, Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina, USA.
3Comprehensive Cancer Centers of Nevada, Henderson, Nevada, USA.
4Optellum Ltd, Oxford, UK annika.rings@optellum.com.
5Optellum Ltd, Oxford, UK.
6The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
7The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Abstract

AIM: This study aims to evaluate the effectiveness of combined artificial intelligence (AI)-based tools for early patient identification, risk stratification and tracking in increasing the follow-up rate of incidentally detected lung nodules, potentially leading to earlier diagnoses of lung cancer, particularly non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: We conducted a retrospective…

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