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Peer-Reviewed Publication
Stat Med2025;44(25-27):e70290.November 1, 2025Journal Article

Model-Twin Randomization (MoTR) for Estimating the Recurring Individual Treatment Effect.

Eric J Daza1, Igor Matias2, Logan Schneider3
1Stats-of-1, Evidation, USA.
2University of Geneva, Geneva, Switzerland.
3Stanford Medicine, Alphabet, USA.

Abstract

Temporally dense single-person "small data" have become widely available thanks to mobile apps and wearable sensors. Many caregivers and self-trackers want to use these data to help a specific person change their behavior to achieve desired health outcomes. Ideally, this involves discerning possible causes from correlations using that person's own observational time series data. In this paper, we…

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