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Peer-Reviewed Publication
Sleep2026;49(4)April 16, 2026Journal Article

The Insomnia EEG Score: a new tool for the classification of people with poor sleep.

Jay Pathmanathan1, David Little1, Kolia Sadeghi1, Tobias Di Marco2, David Kleinschmidt1, Jayne Nerrie1, Nurkurniati Tjiptarto1, Alex Arslan1, Jeffrey Hubbard2, Antonio Olivieri2, Corey B Puryear1, M Brandon Westover1, Jacob Donoghue1
1Beacon Biosignals Inc., Boston, MA 02210, United States.
2Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, 4123 Allschwil, Switzerland.

Abstract

Quantitative features could help objectively identify and grade insomnia severity, though there is currently no pathophysiological biomarker of insomnia. In this study, we used the largest cohort of individuals with and without insomnia to date to train a model capable of distinguishing people with insomnia from those without insomnia. We identified 720 spectral, 606 spindle, and 16 macro-architec…

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