Peer-Reviewed Publication
Pain Manag Nurs2026;27(3):295-307.June 1, 2026Journal Article

Autonomic Parameters Correlated to Acute Postoperative Pain in the Postanesthesia Care Unit: A Systematic Review.

Antonio Jorge Forte1, Francisco R Avila2, Sahar Borna2, Cesar A Gomez-Cabello2, Sophia M Pressman2, Syed Ali Haider2, Rickey E Carter3, Davide Giardi4, Charles J Bruce4, Christopher J McLeod4
1Division of Plastic Surgery, Mayo Clinic, Jacksonville, FL; Center for Digital Health, Mayo Clinic, Rochester, MN. Electronic address: ajvforte@yahoo.com.br.
2Division of Plastic Surgery, Mayo Clinic, Jacksonville, FL.
3Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL.
4Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, FL.

Abstract

INTRODUCTION: Current pain scoring systems are being replaced by sensor-derived physiological parameters responding to autonomic changes (i.e., autonomic parameters such as heart rate variability and pupillary diameter) that quantify pain intensity at a specific moment. However, evidence supporting their use in postoperative patients is scarce. This review aims to analyze the correlation between a…

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