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Peer-Reviewed Publication
Heart Rhythm2026;23(2):e200-e208.February 1, 2026Journal Article

Relationship of symptom frequency and symptom-rhythm correlation to arrhythmia type and time to detection: Insights from ambulatory electrocardiogram monitoring in over 1 million patients.

Anthony J Battisti1, Relana Pinkerton1, Vladimir Fokin1, Brent Wright1, Jay Alexander1, Ronald G Berger2, Mintu P Turakhia3
1iRhythm Technologies Incorporated, San Francisco, California.
2iRhythm Technologies Incorporated, San Francisco, California; Endeavor Health, Bannockburn, Illinois.
3iRhythm Technologies Incorporated, San Francisco, California; Stanford University School of Medicine (Cardiovascular Medicine), Stanford, California. Electronic address: mintu@stanford.edu.

Abstract

BACKGROUND: Arrhythmias are challenging to detect owing to their intermittent nature and variability in symptom reporting. Although long-term continuous monitoring (≤14 days) yields more diagnoses than short-term (Holter) monitoring (≤48 hours), Holter is often preferred by clinicians and payors for frequent symptoms despite limited evidence linking symptom frequency to optimal monitoring duration…

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