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Peer-Reviewed Publication
J Am Med Inform Assoc2026;33(2):336-346.February 1, 2026Journal Article

Re-identification risk for common privacy preserving patient matching strategies when shared with de-identified demographics.

Austin Eliazar1, James Thomas Brown1, Sara Cinamon1, Murat Kantarcioglu2, Bradley Malin3,4,5
1HealthVerity Inc., Philadelphia, PA 19103, United States.
2Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, United States.
3Department of Biomedical Informatics, School of Medicine, Vanderbilt University Medical Center, Nashville, TN 37235, United States.
4Department of Biostatistics, School of Medicine, Vanderbilt University Medical Center, Nashville, TN 37235, United States.
5Department of Computer Science, School of Engineering, Vanderbilt University, Nashville, TN 37235, United States.

Abstract

OBJECTIVE: Privacy preserving record linkage (PPRL) refers to techniques used to identify which records refer to the same person across disparate datasets while safeguarding their identities. PPRL is increasingly relied upon to facilitate biomedical research. A common strategy encodes personally identifying information for comparison without disclosing underlying identifiers. As the scale of resea…

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