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Peer-Reviewed Publication
J Psoriasis Psoriatic Arthritis2025;24755303251387099.October 8, 2025Journal Article

A Trial of Coach-Supported, Smartphone-Delivered Cognitive Behavioral Therapy for Psoriasis With Comorbid Depression.

John S Barbieri1, Megan H Noe1,2, Nora Bensellam1, Phoebe Holz3, Bruna G O Wafae1, Ellen Esther Anshelevich1,4, Jasmine N Williams3, Ivar Snorrason3, Hilary Weingarden3, Oliver Harrison5, Sabine Wilhelm3
1Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
2Sanofi, Boston, MA, USA.
3Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
4Hackensack Meridian School of Medicine, Nutley, NJ, USA.
5Koa Health Limited, London, UK.

Abstract

BACKGROUND: Psoriasis is associated with increased risk of depression. Although cognitive behavioral therapy (CBT) is an evidence-based treatment, access remains limited. OBJECTIVES: To evaluate the feasibility, acceptability, and preliminary efficacy of a smartphone-delivered, coach-led CBT program for depression among individuals with psoriasis. METHODS: This single-arm, 8-week pilot study (Mi…

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