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Peer-Reviewed Publication
J Clin Pathol2025;78(10):691-696.September 18, 2025Journal Article

Use of quality checks and processes across digital histopathology: an initial survey from the Bigpicture consortium.

Hayley Pye1, David S Brettle2, Caitríona Lyons3, Fauve Versaevel4, Erio Barale-Thomas4, Kurt Zatloukal5, Darren Treanor2,6,
1National Pathology Imaging Co-operative, Leeds Teaching Hospitals NHS Trust, Leeds, UK hayley.pye@nhs.net.
2National Pathology Imaging Co-operative, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
3Deciphex Ltd, Dublin, Ireland.
4A Johnson & Johnson Company, Janssen Pharmaceutica NV, Beerse, Belgium.
5Institute of Pathology, Medical University of Graz, Graz, Austria.
6Department of Clinical and Experimental Medicine, Linkopings Universitet, Linköping, Sweden.

Abstract

AIMS: In the end-to-end digital pathology workflow, variability can be introduced at each step, resulting in differences in the final image dataset. The effectiveness of quality control processes at each step of the workflow will impact the extent and relevance of this variability. METHODS: To assess the maturity of whole slide imaging (WSI) quality processes for the whole digital pathology workf…

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