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Peer-Reviewed Publication
Schizophr Bull2026;52(2)March 7, 2026Journal Article

Economic Burden Associated with Negative Symptoms Identified Through Natural Language Processing Among Patients with Schizophrenia in the United States.

Jerome Vaccaro1, Mona Nili2, Pin Xiang2, James K Nelson3, Cory Pack3, Randall Thompson3, Joe Vasey3, Joseph Parks4
1RightPath HC, Millerton, NY 12546, United States.
2Boehringer Ingelheim Pharmaceutical Inc, Ridgefield, CT 06877, United States.
3Veradigm Health, Raleigh, NC 27609, United States.
4National Council for Behavioral Wellbeing, Washington, DC 20005, United States.

Abstract

BACKGROUND AND HYPOTHESIS: The objective of this study was to identify documented negative symptoms of schizophrenia using natural language processing (NLP) and to characterize treatment patterns, healthcare resource utilization (HCRU), and costs among this patient population. STUDY DESIGN: This US retrospective cohort study used electronic health records (EHR) linked to administrative claims dat…

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