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Peer-Reviewed Publication
J Parkinsons Dis2025;15(3):630-645.May 1, 2025Journal Article

Digital health technology for Parkinson's disease with comprehensive monitoring and artificial intelligence-enabled haptic biofeedback for bulbar dysfunction.

Shuai Xu1,2,3, Cagla Kantarcigil4, Rabab Rangwala5, Abigail Nellis5, Keum San Chun1, Dylan Richards1, Ignacio Albert-Smet1, Matthew Keller1, Hope Chen6, Joy Huang6, Shiv Patel1, Albert Yang1, Aejin Shon1, Jacqueline Topping1, Jessica Walter7, Sarah Coughlin1, Hyoyoung Jeong8, Jong Yoon Lee1, Bonnie Martin-Harris5,9
1Sibel Health, Chicago, IL, USA.
2Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
3Querrey Simpson Institute for Bioelectronics, McCormick School of Engineering and Applied Sciences, Northwestern University, Evanston, IL, USA.
4Department of Speech and Hearing Science, The Ohio State University, Columbus, OH, USA.
5Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, IL, USA.
6Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
7Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
8Department of Electrical Engineering, University of California Davis, Sacramento, CA, USA.
9Otolaryngology - Head & Neck Surgery, Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Abstract

BackgroundParkinson's disease (PD) is the second most prevalent neurodegenerative disorder with broad manifestations of motor and non-motor symptoms. While significant progress has been made in assessing motor dysfunction through wearable sensors, less attention has been directed towards bulbar issues like swallowing difficulties.ObjectiveWe introduce a digital health solution leveraging advanced…

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