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Peer-Reviewed Publication
J Psychiatr Res2025;184216-223.April 1, 2025Journal Article

Psychometric properties of the Federal Unit Scale for general psychopathology screening without iatrogenic effects.

Tyler M Moore1, Kathryn Walker2, Franz Hell3, Grayson Rosenblad4, Andrew Cutler3, Adam R Teed3, Maria Coté J Auil5, Rex Jung6, Shobi S Ahmed3
1Sama Therapeutics, Cambridge, MA, 02141, USA; Department of Psychiatry, Brain Behavior Laboratory, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; Lifespan Brain Institute (LiBI), Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, 19104, USA. Electronic address: tyler@sama.ac.
2Revitalist Lifestyle and Wellness, Ltd, Canada.
3Sama Therapeutics, Cambridge, MA, 02141, USA.
4The Webb School, Knoxville, TN, 37923, USA.
5Evidation Health, San Mateo, CA, 94401, USA.
6Sama Therapeutics, Cambridge, MA, 02141, USA; Brain and Behavioral Associates, Albuquerque, NM, 87106, USA.

Abstract

Mental health assessment tools play a crucial role in clinical practice, yet many existing scales risk exacerbating the conditions they aim to measure. This study introduces the Federal Unit Scale (FUS), a novel 5-item scale designed to assess a broad range of affect and traits capturing distress tolerance while minimizing potentially triggering language. The FUS was developed with a focus on comb…

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