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Peer-Reviewed Publication
Appl Clin Inform2025;16(3):575-582.May 1, 2025Journal Article

Challenges to Reduce Alert Burden Using Current Decision Support Infrastructure in Two Commercial EHR Systems: Lessons Learned and Path Forward.

Tiago K Colicchio1, David ElHalta2, Guilherme Del Fiol3, Kensaku Kawamoto3, Howard R Strasberg4, James J Cimino1
1Department of Biomedical Informatics and Data Science, University of Alabama at Birmingham, Birmingham, Alabama, United States.
2Department of Pharmacy Services, University of Utah, Salt Lake City, Utah, United States.
3Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah, United States.
4Clinical Effectiveness, Wolters Kluwer Health, San Diego, California, United States.

Abstract

Despite the proven usefulness of appropriate clinical decision support (CDS) alerts, many CDS systems fire excessive, clinically irrelevant alerts that are often ignored by clinicians. We have developed a method to suppress false-positive alerts based on prior drug tolerance but encountered substantial barriers to integrating the method into widely adopted commercial electronic health record (EHR)…

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