Peer-Reviewed Publication
Nat Med2025;31(3):925-931.March 1, 2025Journal Article
Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography.
L S Johnson1,2, P Zadrozniak3, G Jasina3, A Grotek-Cuprjak3, J G Andrade4, E Svennberg5,6, S Z Diederichsen7, W F McIntyre8,9, S Stavrakis10, J Benezet-Mazuecos11, P Krisai12, Z Iakobishvili13,14, A Laish-Farkash13, S Bhavnani15, E Ljungström16, J Bacevicius17, N L van Vreeswijk18, M Rienstra18, R Spittler19, J A Marx19, A Oraii8, A Miracle Blanco11, A Lozano11, I Mustafina10,20, S Zafeiropoulos21,22, R Bennett4, J Bisson23, D Linz24,25, Y Kogan13, E Glazer13, G Marincheva13, M Rahkovich13, E Shaked13, M H Ruwald26, K Haugan27, J Węcławski3, G Radoslovich28, S Jamal28,29, A Brandes30,31, P T Matusik32,33, M Manninger34, P B Meyre12, S Blum12, A Persson35,36, A Måneheim35,36, P Hammarlund37, A Fedorowski35,5,38, T Wodaje5,38, C Lewinter5,38,39, V Juknevicius17, R Jakaite17, C Shen15, T Glotzer28,29, P Platonov16,40, G Engström35, A P Benz8,19, J S Healey8,9
1Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden. linda.johnson@med.lu.se.
2Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. linda.johnson@med.lu.se.
3Medicalgorithmics S.A., Warsaw, Poland.
4Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
5Karolinska Institutet, Stockholm, Sweden.
6Department of Medicine Huddinge, Karolinska University Hospital, Stockholm, Sweden.
7Department of Cardiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
8Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
9Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
10University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
11Cardiology Department Hospital Universitario La Luz, Madrid, Spain.
12Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, University of Basel, Basel, Switzerland.
13Department of Cardiology, Assuta Ashdod University Hospital, Ben-Gurion University of the Negev, Ashdod, Israel.
14Department of Cardiology, Clalit Health Services, Tel Aviv Jaffa District, Israel.
15Division of Cardiology, Scripps Clinic, San Diego, CA, USA.
16Arrhythmia Clinic, Skåne University Hospital, Lund, Sweden.
17Clinic of Heart and Vessel Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
18Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
19Department of Cardiology, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Mainz, Germany.
20Department of Internal Diseases, Bashkir State Medical University, Ufa, Russia.
21Feinstein Institutes for Medical Research at Northwell Health, Manhasset, NY, USA.
22Department of Cardiology, University Hospital of Zurich, Zürich, Switzerland.
23Department of Cardiology, Centre hospitalier de l'Université de Montréal-Université de Montréal, Montréal, Quebec, Canada.
24Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, The Netherlands.
25Faculty of Health and Medical Sciences, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
26Department of Cardiology, Gentofte Hospital, Hellerup, Denmark.
27Department of Cardiology, Zealand University Hospital, Roskilde, Denmark.
28Hackensack University Medical Center, Hackensack, NJ, USA.
29Hackensack Meridian School of Medicine, Nutley, NJ, USA.
30Department of Cardiology, Esbjerg Hospital-University Hospital of Southern Denmark, Esbjerg, Denmark.
31Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark.
32Department of Electrocardiology, Institute of Cardiology, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.
33St. John Paul II Hospital, Kraków, Poland.
34Division of Cardiology, Department of Medicine, Medical University of Graz, Graz, Austria.
35Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.
36Department of Clinical Physiology, Skåne University Hospital, Malmö, Sweden.
37Department of Cardiology, Helsingborg Hospital, Helsingborg, Sweden.
38Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
39University of Glasgow, University of Glasgow, Institute of Wellbeing, Glasgow, UK.
40Department of Clinical Sciences, Lund University, Lund, Sweden.
Abstract
Developments in ambulatory electrocardiogram (ECG) technology have led to vast amounts of ECG data that currently need to be interpreted by human technicians. Here we tested an artificial intelligence (AI) algorithm for direct-to-physician reporting of ambulatory ECGs. Beat-by-beat annotation of 14,606 individual ambulatory ECG recordings (mean duration = 14 ± 10 days) was performed by certified E…
Create a free account to keep reading
Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.
Want unlimited research access? See Pro plans