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Sci Rep2025;15(1):4524.February 6, 2025Journal Article

3D echocardiography derived reference values and determinants of left ventricular twist and torsion from the population-based STAAB cohort study.

Julia Napp1,2, Götz Gelbrich3,4, Floran Sahiti1,2, Vladimir Cejka1, Dora Pelin1, Lena Schmidbauer3, Mengmeng Chen1, Niklas Hitschrich5, Marcus Schreckenberg5, Stefan Frantz1,2, Peter U Heuschmann3,4,6, Stefan Störk1,2, Caroline Morbach7,8
1Academic Core Lab Ultrasound-Based Cardiovascular Imaging, Department Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Am Schwarzenberg 15, 97078, Würzburg, Germany.
2Department of Medicine I, University Hospital Würzburg, Würzburg, Germany.
3Institute of Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.
4Clinical Trial Center, University Hospital Würzburg, Würzburg, Germany.
5TOMTEC Imaging Systems GmbH, Unterschleißheim, Germany.
6Institute for Medical Data Sciences, University Hospital Würzburg, Würzburg, Germany.
7Academic Core Lab Ultrasound-Based Cardiovascular Imaging, Department Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Am Schwarzenberg 15, 97078, Würzburg, Germany. Morbach_C@ukw.de.
8Department of Medicine I, University Hospital Würzburg, Würzburg, Germany. Morbach_C@ukw.de.
PubMed PMC DOI PDF

Abstract

Left ventricular (LV) rotational function parameters provide in-depth information about LV mechanical function as well as prognostic information. Using three-dimensional (3D) echocardiography, we identified determinants of LV "twist" and "torsion", and established reference values using a large population-based cohort. 3D echocardiography images were recorded in n = 2803 subjects within the prospe…

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