Health AI Central
Peer-Reviewed Publication
J Diabetes Sci Technol2026;20(3):942-953.May 1, 2026Journal Article

A Performance-Based Adaptation Index for Automated Insulin Delivery Systems.

Jenny L Diaz C1,2, Patricio Colmegna1,3, Elliot Pryor1, Marc D Breton1
1Center for Diabetes Technology, School of Medicine, University of Virginia, Charlottesville, VA, USA.
2Insulet Co., Acton, MA, USA.
3Dexcom Inc, San Diego, CA, USA.
PubMed PMC DOI PDF

Abstract

BACKGROUND: Automated insulin delivery (AID) algorithms can benefit from tuning of their aggressiveness to meet individual needs, as insulin requirements vary among and within users. We introduce the Performance-Based Adaptation Index (PAI), a tool designed to enable automatic adjustment of an AID system aggressiveness based on continuous glucose monitoring (CGM) metrics. METHODS: PAI integrates…

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