Survival of intact bovine whey proteins across in vivo and simulated static in vitro models of the adult gastrointestinal tract.

Suwimon Sutantawong¹, Bum Jin Kim², Yunyao Qu³, David C Dallas⁴

¹Department of Food Science & Technology, Oregon State University, Corvallis, OR 97331, USA. Electronic address: noom.sutantawong@oregonstate.edu.

²Nutrition Program, College of Health, Oregon State University, Corvallis, OR 97331, USA. Electronic address: bumjin.kim@oregonstate.edu.

³Department of Food Science & Technology, Oregon State University, Corvallis, OR 97331, USA. Electronic address: yunyao.qu@oregonstate.edu.

⁴Department of Food Science & Technology, Oregon State University, Corvallis, OR 97331, USA; Nutrition Program, College of Health, Oregon State University, Corvallis, OR 97331, USA. Electronic address: Dave.Dallas@oregonstate.edu.

PubMed DOI

Abstract

Bovine whey contains bioactive proteins that could benefit consumer health, but their intact bioactivity depends on their ability to survive the digestive process and remain intact to their sites of action. Our study assessed whey protein degradation in the adult human jejunum after whey protein isolate ingestion and during static in vitro gastric and intestinal digestions, using LC-MS/MS-based pr…

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